Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 7/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.61 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.61 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.61 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.61 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.61 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.61 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.61 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.61 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.61 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.61 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.61 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.61 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.61 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.61 |
| ▸ | PSMB3 | P49720 | 3/20 | 0.61 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.61 |
| ▸ | PSMA6 | P60900 | 3/20 | 0.61 |
| ▸ | PSMA8 | Q8TAA3 | 3/20 | 0.61 |
| ▸ | PSMB7 | Q99436 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850320 | 0.90 | LONP1 (0.62) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6845978 | 0.87 | LONP1 (0.59) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6848918 | 0.87 | LONP1 (0.56) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6849892 | 0.86 | LONP1 (0.58) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6850382 | 0.86 | LONP1 (0.57) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6845955 | 0.85 | LONP1 (0.59) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6848816 | 0.85 | LONP1 (0.56) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6850311 | 0.85 | LONP1 (0.56) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6851522 | 0.85 | LONP1 (0.56) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL6848902 | 0.85 | LONP1 (0.56) | LONP1PSMB5PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252178-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001040262-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-07 | — | — | WO | disclosed |