Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387975 | 0.86 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL9312889 | 0.84 | PTPN1 (0.40) | CYP1A2CYP2C9CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL9313695 | 0.78 | ACP3 (0.40) | SMN1; SMN2HIF1AKIF11 | |
| SCHEMBL11020720 | 0.74 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19HIF1AMAPK1 | |
| SCHEMBL9063882 | 0.73 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL27963095 | 0.72 | CYP2C9 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL9312893 | 0.71 | PTPN1 (0.39) | CYP1A2SMN1; SMN2CYP3A4KIF11PTPN1 | |
| SCHEMBL698616 | 0.70 | TSHR (0.48) | CYP1A2CYP2C19SMN1; SMN2HIF1AMAPK1 | |
| SCHEMBL7095560 | 0.70 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL19744359 | 0.70 | TDP1 (0.39) | SMN1; SMN2MAPK1TAAR1HTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3173898-A | — | — | None | — | — | JP | disclosed |
| US-5389612-A | Treating infections caused by clostridium histolyticum and pseudomonas aeruginosa; enzyme inhibitors | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1995-02-14 | — | — | US | disclosed |
| EP-0565450-A1 | Use of peptide derivatives for the manufacture of medicaments inhibiting endopeptidases 24.15 and 24.16 | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-10-13 | — | — | EP | disclosed |
| JP-H03173898-A | NEW PHOSPHONIC PEPTIDE DERIVATIVE USEFUL AS INHIBITOR OF BACTERIAL COLLAGENASE | COMMISS ENERG ATOM | 1991-07-29 | — | — | JP | disclosed |