Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394880 | 0.91 | PDE4A (0.73) | PDE4AKCNH2 | |
| SCHEMBL7399611 | 0.89 | PDE4A (0.63) | PDE4AKCNH2 | |
| SCHEMBL7963639 | 0.85 | PDE4A (0.65) | PDE4AKCNH2 | |
| SCHEMBL7951554 | 0.85 | PDE4A (0.63) | PDE4AKCNH2 | |
| SCHEMBL7394881 | 0.84 | PDE4A (0.62) | PDE4AKCNH2 | |
| SCHEMBL7397571 | 0.79 | PDE4A (0.56) | PDE4AKCNH2 | |
| SCHEMBL7398318 | 0.79 | PDE4A (0.68) | PDE4AKCNH2 | |
| Ethane SCHEMBL7961688 | 0.78 | PDE4A (0.67) | PDE4AKCNH2 | |
| SCHEMBL7462478 | 0.78 | PDE4A (0.64) | PDE4AKCNH2 | |
| SCHEMBL7951481 | 0.78 | PDE4A (0.61) | PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157007-A1 | PDE IV INHIBITING COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT | MERCK FROSST CANADA INC. (CA) | 2001-11-28 | — | — | EP | disclosed |
| US-6204275-B1 | PDE IV inhibiting compounds, compositions and methods of treatment | MERCK FROSST CANADA & CO. (CA) | 2001-03-20 | — | — | US | disclosed |
| WO-2000050402-A1 | PDE IV INHIBITING COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT | MERCK FROSST CANADA & CO. (CA) | 2000-08-31 | — | — | WO | disclosed |