Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | UGCG | Q16739 | 2/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556046 | 0.98 | GBA1 (0.45) | GBA1UGCGGBA2MAOBMAOA | |
| SCHEMBL7393834 | 0.91 | CYP3A4 (0.50) | GBA1UGCGGBA2CYP3A4HSD17B10 | |
| SCHEMBL11777492 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 | |
| SCHEMBL11774893 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 | |
| SCHEMBL11773030 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 | |
| SCHEMBL11772170 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 | |
| SCHEMBL11775440 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 | |
| SCHEMBL11774715 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 | |
| SCHEMBL11776870 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 | |
| SCHEMBL11774160 | 0.90 | CYP3A4 (0.49) | GBA1UGCGGBA2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |