Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065981 | 1.00 | PAOX (0.55) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL28375298 | 0.91 | SOAT1 (0.59) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL16620178 | 0.91 | SOAT1 (0.59) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL28928375 | 0.91 | SOAT1 (0.59) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL23929253 | 0.91 | SOAT1 (0.53) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL28816812 | 0.91 | SOAT1 (0.59) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL28888916 | 0.91 | SOAT1 (0.59) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL25185288 | 0.91 | SOAT1 (0.59) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL22834949 | 0.91 | SOAT1 (0.53) | PAOXSOAT1MEN1FAAHTP53 | |
| SCHEMBL28164599 | 0.91 | SOAT1 (0.59) | PAOXSOAT1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252178-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001040262-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-07 | — | — | WO | disclosed |