Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 11/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394846 | 0.79 | HPRT1 (0.46) | HPRT1PNP | |
| SCHEMBL3126819 | 0.77 | ADORA2A (0.60) | HPRT1PNP | |
| SCHEMBL7397072 | 0.76 | HPRT1 (0.59) | HPRT1PNP | |
| SCHEMBL7374581 | 0.75 | HPRT1 (0.64) | HPRT1PNP | |
| SCHEMBL7399609 | 0.73 | HPRT1 (0.56) | HPRT1PNP | |
| SCHEMBL2979895 | 0.73 | MEN1 (0.68) | HPRT1PNP | |
| SCHEMBL7391726 | 0.72 | HPRT1 (0.59) | HPRT1PNP | |
| SCHEMBL14236049 | 0.72 | PNP (0.56) | PNPAKR1B1 | |
| Leteprinim SCHEMBL6935182 | 0.72 | HPRT1 (0.49) | HPRT1PNP | |
| Leteprinim SCHEMBL6931317 | 0.72 | HPRT1 (0.49) | HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522082-B1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | GLASKY ALVIN J (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0522082-A4 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | — | 1993-06-09 | — | — | EP | disclosed |
| EP-0522082-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE. | GLASKY ALVIN J (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5091432-A | Synergistic | SPECTRUM PHARMACEUTICALS, INC. | 1992-02-25 | — | — | US | disclosed |
| WO-1991014434-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | GLASKY ALVIN J (US) | 1991-10-03 | — | — | WO | disclosed |