Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651847 | 1.00 | NPY5R (0.40) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL8653693 | 0.93 | NPY5R (0.42) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL8656621 | 0.93 | NPY5R (0.42) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL8653695 | 0.93 | NPY5R (0.42) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL7329129 | 0.91 | KMT2A (0.46) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL8652209 | 0.91 | KMT2A (0.46) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL7335350 | 0.89 | PPARA (0.46) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL7327712 | 0.89 | PPARA (0.46) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL7328072 | 0.89 | PPARA (0.46) | NPY5REPHX2KDM1AKMT2AL3MBTL1 | |
| SCHEMBL8650717 | 0.89 | NPC1 (0.41) | EPHX2KMT2AL3MBTL1MAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | disclosed |
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |