Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.68 |
| ▸ | CMA1 | P23946 | 2/20 | 0.60 |
| ▸ | CTRC | Q99895 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401405 | 0.90 | ELANE (0.80) | ELANECTRC | |
| SCHEMBL9585315 | 0.89 | ELANE (0.81) | ELANE | |
| SCHEMBL7399121 | 0.88 | ELANE (0.73) | ELANE | |
| SCHEMBL9585729 | 0.87 | ELANE (0.88) | ELANE | |
| SCHEMBL7394477 | 0.87 | ELANE (0.57) | ELANECMA1CTRC | |
| SCHEMBL7392103 | 0.87 | ELANE (0.68) | ELANE | |
| SCHEMBL7402103 | 0.84 | ELANE (0.79) | ELANECTRC | |
| SCHEMBL7394990 | 0.84 | ELANE (0.79) | ELANECTRC | |
| SCHEMBL7404982 | 0.83 | CMA1 (0.65) | ELANECMA1CTRC | |
| SCHEMBL9584333 | 0.82 | ELANE (0.91) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636141-A1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS. | ZENECA LTD (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021210-A1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |