Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.56 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.56 |
| ▸ | CPA3 | P15088 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7396350 | 1.00 | MME (0.56) | MMEACEALDH1A1MEN1KMT2A | |
| SCHEMBL10572943 | 0.99 | MME (0.57) | MMEACEALDH1A1MEN1KMT2A | |
| SCHEMBL7425850 | 0.87 | MME (0.52) | MMEACEALDH1A1MEN1KMT2A | |
| SCHEMBL10395910 | 0.84 | MEN1 (0.56) | ALDH1A1MEN1KMT2AFOLH1CFD | |
| SCHEMBL10395908 | 0.84 | MEN1 (0.56) | ALDH1A1MEN1KMT2AFOLH1CFD | |
| SCHEMBL7432719 | 0.83 | MME (0.50) | MMEACEALDH1A1MEN1KMT2A | |
| SCHEMBL7434438 | 0.83 | GRIK1 (0.55) | MMEACEALDH1A1MEN1KMT2A | |
| SCHEMBL9724964 | 0.83 | MME (0.58) | MMEACEALDH1A1MEN1KMT2A | |
| SCHEMBL7438446 | 0.83 | PTPN1 (0.52) | MMEACEALDH1A1MEN1KMT2A | |
| SCHEMBL9724871 | 0.82 | MME (0.57) | MMEACEALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364767-A1 | Mercapto-acylamino acids useful in the treatment of cardiovascular disorders and as analgesics | SCHERING CORPORATION (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1990003364-A1 | MERCAPTO-ACYLAMINO ACIDS USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISORDERS AND AS ANALGESICS | SCHERING CORPORATION (US) | 1990-04-05 | — | — | WO | disclosed |
| US-4879309-A | ENKEPHALINASE INHIBITORS | SCHERING CORPORATION (US) | 1989-11-07 | — | — | US | disclosed |