Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397615 | 0.95 | ELANE (0.80) | ELANECTRC | |
| SCHEMBL7401169 | 0.91 | ELANE (0.81) | ELANECTRC | |
| SCHEMBL7394093 | 0.90 | ELANE (0.84) | ELANECTRC | |
| SCHEMBL7399847 | 0.90 | ELANE (0.84) | ELANECTRC | |
| SCHEMBL7396072 | 0.89 | ELANE (0.84) | ELANECTRC | |
| SCHEMBL7397369 | 0.88 | ELANE (0.67) | ELANECTRC | |
| SCHEMBL9583963 | 0.88 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL7402103 | 0.87 | ELANE (0.79) | ELANECTRC | |
| SCHEMBL7398795 | 0.87 | ELANE (0.79) | ELANECTRC | |
| SCHEMBL7394990 | 0.87 | ELANE (0.79) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441960-A | 1-pyrimidinylacetamide human leukocyte elastate inhibitors | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0636141-A1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS. | ZENECA LTD (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021210-A1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |