Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.73 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.60 |
| ▸ | CCKBR | P32239 | 13/20 | 0.58 |
| ▸ | CCKAR | P32238 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CASP4 | P49662 | 1/20 | 0.54 |
| ▸ | CASP5 | P51878 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP9 | P55211 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.54 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069917 | 0.97 | EDNRA (0.69) | EDNRAMAGI3CCKBRCCKARCASP1 | |
| SCHEMBL7396826 | 0.95 | EDNRA (0.69) | EDNRAMAGI3CCKBRCCKARCASP1 | |
| SCHEMBL7396823 | 0.95 | EDNRA (0.69) | EDNRAMAGI3CCKBRCCKARCASP1 | |
| SCHEMBL7400880 | 0.95 | EDNRA (0.69) | EDNRAMAGI3CCKBRCCKARCASP1 | |
| SCHEMBL30533185 | 0.93 | EDNRA (0.82) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL7395342 | 0.92 | EDNRA (0.81) | EDNRAMAGI3ECE1 | |
| SCHEMBL7395344 | 0.92 | EDNRA (0.81) | EDNRAMAGI3ECE1 | |
| SCHEMBL7401708 | 0.91 | EDNRA (0.61) | EDNRAMAGI3CCKBRCCKARCASP1 | |
| SCHEMBL7397607 | 0.91 | EDNRA (0.72) | EDNRAMAGI3CCKBRCCKARCASP1 | |
| SCHEMBL9069770 | 0.91 | MAGI3 (0.68) | EDNRAMAGI3CCKBRCCKARCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | claimed |
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |