Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 4/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.36 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 2/20 | 0.33 |
| ▸ | PRKCH | P24723 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397468 | 1.00 | GRM2 (0.42) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7394672 | 0.87 | MAPT (0.44) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7394664 | 0.87 | MAPT (0.44) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7394811 | 0.87 | MAPT (0.44) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7394671 | 0.87 | MAPT (0.44) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7394809 | 0.87 | MAPT (0.44) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7405668 | 0.81 | GRM2 (0.42) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7401646 | 0.81 | GRM2 (0.42) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7405665 | 0.81 | GRM2 (0.42) | GRM2TSHRHSD17B10PRKCAPRKCD | |
| SCHEMBL7401650 | 0.81 | GRM2 (0.42) | GRM2TSHRHSD17B10PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |