Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.71 |
| ▸ | ECE1 | P42892 | 12/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512696 | 1.00 | ACE (0.71) | ACEECE1ALOX15 | |
| SCHEMBL5481232 | 1.00 | ACE (0.71) | ACEECE1ALOX15 | |
| SCHEMBL8725890 | 1.00 | ACE (0.71) | ACEECE1ALOX15 | |
| SCHEMBL30051826 | 0.98 | ACE (0.68) | ACEECE1ALOX15 | |
| SCHEMBL29555460 | 0.96 | ACE (0.66) | ACEECE1ALOX15 | |
| SCHEMBL7404624 | 0.95 | ACE (0.64) | ACEECE1ALOX15 | |
| SCHEMBL30080510 | 0.95 | ACE (0.64) | ACEECE1ALOX15 | |
| SCHEMBL7404621 | 0.95 | ACE (0.64) | ACEECE1ALOX15 | |
| SCHEMBL30052487 | 0.94 | ACE (0.63) | ACEECE1 | |
| SCHEMBL30725664 | 0.94 | ACE (0.70) | ACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | claimed |