SCHEMBL7397661

SCHEMBL7397661

COC(=O)C(Cl)=NC1CC1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15395937 0.69
SCHEMBL6292154 0.69
SCHEMBL8024507 0.69
SCHEMBL20381047 0.67
SCHEMBL3103329 0.67
SCHEMBL7479642 0.67
SCHEMBL8377003 0.67
SCHEMBL8749615 0.66
SCHEMBL25784943 0.65
SCHEMBL3025 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648205-B1 PEPTIDYL DERIVATIVES AS METALLOPROTEINASE INHIBITORS CELLTECH THERAPEUTICS LTD (GB) 1999-07-14 EP disclosed
US-5714491-A ANTICANCER AND ANTITUMOR AGENT CELLTECH THERAPEUTICS LIMITED (GB) 1998-02-03 US disclosed
EP-0648205-A1 PEPTIDYL DERIVATIVES AS METALLOPROTEINASE INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1995-04-19 EP disclosed
WO-1994025434-A1 PEPTIDYL DERIVATIVES AS METALLOPROTEINASE INHIBITORS CELLTECH LIMITED (GB) 1994-11-10 WO disclosed