Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395668 | 0.92 | KLK5 (0.75) | BACE1KLK5 | |
| SCHEMBL9394616 | 0.88 | KLK5 (0.62) | BACE1KLK5 | |
| SCHEMBL5619596 | 0.88 | KLK5 (0.62) | BACE1KLK5 | |
| SCHEMBL7402507 | 0.88 | BACE1 (0.61) | BACE1KLK5 | |
| SCHEMBL7400784 | 0.88 | BACE1 (0.61) | BACE1KLK5 | |
| SCHEMBL7400774 | 0.87 | KLK5 (0.58) | BACE1KLK5 | |
| SCHEMBL7392856 | 0.84 | KLK5 (0.67) | BACE1KLK5 | |
| SCHEMBL7294584 | 0.83 | PSEN1 (0.71) | BACE1KLK5 | |
| SCHEMBL5620574 | 0.82 | BACE1 (0.55) | BACE1KLK5 | |
| SCHEMBL5620577 | 0.82 | BACE1 (0.55) | BACE1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009132-A1 | HIV PROTEASE INHIBITORS CONTAINING GUANIDINE | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-13 | — | — | WO | disclosed |