Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395719 | 0.90 | GAA (0.34) | KDM4EGAARECQLCASP3BRD4 | |
| SCHEMBL7392955 | 0.89 | CDC25A (0.37) | — | |
| SCHEMBL7388119 | 0.84 | — | — | |
| SCHEMBL7386861 | 0.74 | CDC25A (0.32) | — | |
| SCHEMBL7398238 | 0.74 | GAA (0.34) | KDM4EGAARECQLBRD4MEN1 | |
| SCHEMBL8702342 | 0.73 | MEN1 (0.32) | POLBHPGDMEN1KMT2A | |
| SCHEMBL7395911 | 0.72 | RECQL (0.36) | KDM4EGAARECQLHPGDBRD4 | |
| SCHEMBL7395913 | 0.71 | GAA (0.35) | KDM4EGAARECQLBRD4MEN1 | |
| SCHEMBL7398242 | 0.70 | GAA (0.33) | KDM4EGAARECQLBRD4MEN1 | |
| SCHEMBL8634227 | 0.68 | GAA (0.37) | KDM4EGAARECQLBRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0592791-A2 | Tricyclic compounds and peptide derivatives thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1994-04-20 | — | — | EP | disclosed |