Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.69 |
| ▸ | F2 | P00734 | 12/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.69 |
| ▸ | F9 | P00740 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836066 | 0.85 | F10 (0.77) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3829612 | 0.85 | F10 (0.70) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7230488 | 0.82 | F2 (0.67) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3830187 | 0.82 | F10 (0.72) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3830234 | 0.81 | F10 (0.74) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3829898 | 0.81 | F10 (0.77) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3836073 | 0.81 | F10 (0.70) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3831575 | 0.81 | F10 (0.63) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3831605 | 0.81 | F10 (0.76) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3831563 | 0.81 | F10 (0.75) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020357-A | CARDIOVASCULAR DISORDERS; ANTCOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-02-01 | — | — | US | claimed |