Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.55 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381715 | 1.00 | GRM1 (0.68) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL13816269 | 0.85 | ACE2 (0.61) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL661700 | 0.81 | GRM1 (1.00) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL29393013 | 0.81 | GRM1 (1.00) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL1078997 | 0.81 | GRM1 (1.00) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL2269011 | 0.81 | GRM1 (1.00) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL7575487 | 0.80 | ACE2 (0.56) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL17014695 | 0.79 | ACE2 (0.54) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL7594615 | 0.78 | GRM1 (0.56) | GRM1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL7392560 | 0.78 | GRM1 (0.66) | GRM1MEN1KMT2ACYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807621-A1 | Derivatives of phenylglycine and use thereof as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1997-11-19 | — | — | EP | disclosed |