⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472181 | 1.00 | — | — | |
| SCHEMBL468961 | 0.78 | — | — | |
| SCHEMBL10067852 | 0.78 | — | — | |
| SCHEMBL4291341 | 0.78 | — | — | |
| SCHEMBL1045132 | 0.76 | — | — | |
| SCHEMBL4619445 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL29274073 | 0.76 | PTGS1 (0.46) | — | |
| SCHEMBL8251491 | 0.76 | — | — | |
| SCHEMBL15297100 | 0.74 | — | — | |
| SCHEMBL19696557 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000055156-A1 | SUBSTITUTED AROMATIC AMIDINE DERIVATIVE AND MEDICINAL COMPOSITION COMPRISING THE SAME | C & C RESEARCH LABORATORIES (KR) | 2000-09-21 | — | — | WO | claimed |
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2000055156-A1 | SUBSTITUTED AROMATIC AMIDINE DERIVATIVE AND MEDICINAL COMPOSITION COMPRISING THE SAME | C & C RESEARCH LABORATORIES (KR) | 2000-09-21 | — | — | WO | disclosed |