Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 4/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398919 | 1.00 | KMT2A (0.46) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL7398913 | 1.00 | KMT2A (0.46) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL7398920 | 1.00 | KMT2A (0.46) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL9546745 | 0.92 | KMT2A (0.47) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL9546739 | 0.92 | KMT2A (0.47) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL9546753 | 0.92 | KMT2A (0.47) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL9546491 | 0.89 | KMT2A (0.47) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL9546494 | 0.89 | KMT2A (0.47) | KMT2AMAPK1MEN1PSEN1PSEN2 | |
| SCHEMBL7400064 | 0.89 | PSEN1 (0.51) | KMT2AMAPK1PSEN1PSEN2APH1B | |
| SCHEMBL7400059 | 0.89 | PSEN1 (0.51) | KMT2AMAPK1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632808-A1 | ANTIVIRAL PEPTIDES | Pfizer Limited (GB) | 1995-01-11 | — | — | EP | disclosed |
| WO-1993019059-A1 | ANTIVIRAL PEPTIDES | PFIZER LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |