Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167769 | 1.00 | CHRM2 (0.67) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL3743481 | 0.83 | CHRM2 (0.71) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL3743487 | 0.82 | CHRM2 (0.69) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL5171242 | 0.82 | CHRM2 (0.69) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL1549648 | 0.82 | CHRM2 (0.69) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL21063805 | 0.80 | CHRM2 (0.67) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL16814073 | 0.80 | CHRM2 (0.67) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL1566368 | 0.80 | CHRM2 (0.67) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| (S)-Aceclidine SCHEMBL9146471 | 0.80 | CHRM2 (1.00) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL13470758 | 0.80 | CHRM2 (0.67) | CHRM2CHRM1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117679415-A | Glucoamide synthase inhibitors | 建新公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114929237-A | Trehalose formulations and uses thereof | 西洛斯治疗有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |
| WO-2015089067-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2015-06-18 | — | — | WO | disclosed |
| EP-1461336-B1 | 1-ALKYL-1-AZONIABICYCLO (2.2.2) OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARMA SPA (IT) | 2013-05-22 | — | — | EP | disclosed |
| EP-0885221-A1 | AZABICYCLIC ESTERS OF CARBAMIC ACIDS USEFUL IN THERAPY | Astra Aktiebolag (SE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997030998-A1 | AZABICYCLIC ESTERS OF CARBAMIC ACIDS USEFUL IN THERAPY | ASTRA AKTIEBOLAG (SE) | 1997-08-28 | — | — | WO | disclosed |