Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852059 | 0.95 | CYP1A2 (0.40) | CYP1A2HTTFOLH1ALDH1A1FFAR4 | |
| SCHEMBL29851943 | 0.93 | CYP1A2 (0.39) | CYP1A2HTTFOLH1ALDH1A1FFAR4 | |
| SCHEMBL1114400 | 0.89 | CYP1A2 (0.51) | CYP1A2HTTFOLH1FFAR4FFAR1 | |
| Methoxymethane SCHEMBL29851917 | 0.89 | CYP1A2 (0.40) | CYP1A2HTTFOLH1ALDH1A1FFAR4 | |
| SCHEMBL3286245 | 0.86 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL3621368 | 0.84 | CYP1A2 (0.44) | CYP1A2 | |
| SCHEMBL3283600 | 0.83 | CYP1A2 (0.42) | CYP1A2 | |
| SCHEMBL31710559 | 0.81 | CYP1A2 (0.36) | CYP1A2ALDH1A1 | |
| SCHEMBL12459735 | 0.81 | CYP1A2 (0.46) | CYP1A2 | |
| SCHEMBL13449809 | 0.81 | CYP1A2 (0.46) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022207923-A1 | SUBSTITUTED LACTONES, POLYMERS THEREOF, AND PROCESSES FOR PREPARING SAME | SCE FRANCE (FR) | 2022-10-06 | — | — | WO | disclosed |
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| US-5504106-A | Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |