Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.55 |
| ▸ | CHRNG | P07510 | 1/20 | 0.55 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.55 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159283 | 0.87 | HPGD (0.61) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22151090 | 0.86 | HPGD (0.59) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8802537 | 0.86 | HPGD (0.59) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5448808 | 0.85 | HPGD (0.70) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5747070 | 0.84 | HPGD (0.61) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2159492 | 0.84 | HPGD (0.61) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31360716 | 0.84 | GRN (0.53) | HPGDMEN1KMT2ARAB9ALMNA | |
| SCHEMBL31360502 | 0.84 | GRN (0.53) | HPGDMEN1KMT2ARAB9ALMNA | |
| SCHEMBL4173714 | 0.83 | ATM (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16799699 | 0.82 | PDE5A (0.47) | HPGDNPC1RAB9AGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1376143-A | Carboxylic acid derivatives and adhesion molecule inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2002-10-23 | — | — | CN | disclosed |
| EP-1183238-A1 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069816-A1 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |