Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.59 |
| ▸ | EDNRA | P25101 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 6/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.46 |
| ▸ | BID | P55957 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400060 | 1.00 | MAGI3 (0.59) | MAGI3EDNRAACEMMP1SIRT5 | |
| SCHEMBL7398427 | 0.94 | EDNRA (0.66) | MAGI3EDNRAACEMMP1SIRT5 | |
| SCHEMBL7398428 | 0.94 | EDNRA (0.66) | MAGI3EDNRAACEMMP1SIRT5 | |
| SCHEMBL7400066 | 0.93 | MAGI3 (0.66) | MAGI3EDNRAMMP1SIRT5IL23R | |
| SCHEMBL7400067 | 0.93 | MAGI3 (0.66) | MAGI3EDNRAMMP1SIRT5IL23R | |
| SCHEMBL7400146 | 0.92 | MAGI3 (0.53) | MAGI3EDNRAACEMMP1SIRT5 | |
| SCHEMBL7400150 | 0.92 | MAGI3 (0.53) | MAGI3EDNRAACEMMP1SIRT5 | |
| SCHEMBL30208645 | 0.90 | EDNRA (0.64) | MAGI3EDNRAACEECE1KMT2A | |
| SCHEMBL7495581 | 0.86 | MAGI3 (0.65) | MAGI3EDNRAACEIL23RECE1 | |
| SCHEMBL7495576 | 0.86 | MAGI3 (0.65) | MAGI3EDNRAACEIL23RECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | claimed |
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |