Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449476 | 0.88 | MAPK10 (0.42) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7406970 | 0.88 | MAPK10 (0.38) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7406251 | 0.87 | PLG (0.41) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7401465 | 0.86 | MAPK10 (0.41) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7399046 | 0.85 | MAPK10 (0.39) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7405526 | 0.84 | MAPK10 (0.36) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7408668 | 0.82 | MAPK10 (0.38) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7405026 | 0.82 | MAPK10 (0.40) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7408189 | 0.82 | PLG (0.39) | MAPK10CA1CA2CA7CA9 | |
| SCHEMBL7410608 | 0.80 | MAPK10 (0.36) | MAPK10CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040449-A1 | DIHYDROISOQUINOLINES AS NOVEL PHOSPHODIESTERASE INHIBITORS | ALTANA PHARMA AG (DE) | 2002-05-23 | — | — | WO | disclosed |