Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.64 |
| ▸ | CMA1 | P23946 | 11/20 | 0.63 |
| ▸ | CTRC | Q99895 | 11/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397392 | 0.93 | ELANE (0.62) | ELANECMA1CTRC | |
| SCHEMBL7435414 | 0.93 | ELANE (0.76) | ELANECMA1CTRC | |
| SCHEMBL9143450 | 0.90 | ELANE (0.65) | ELANECMA1CTRC | |
| SCHEMBL7397385 | 0.87 | ELANE (0.68) | ELANECMA1CTRC | |
| SCHEMBL9584648 | 0.87 | ELANE (0.84) | ELANECMA1CTRC | |
| SCHEMBL7398785 | 0.86 | CMA1 (0.67) | ELANECMA1CTRC | |
| SCHEMBL7397088 | 0.85 | ELANE (0.63) | ELANECMA1CTRC | |
| SCHEMBL7397615 | 0.85 | ELANE (0.80) | ELANECTRC | |
| SCHEMBL7404982 | 0.83 | CMA1 (0.65) | ELANECMA1CTRC | |
| SCHEMBL7401169 | 0.81 | ELANE (0.81) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441960-A | 1-pyrimidinylacetamide human leukocyte elastate inhibitors | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0636141-A1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS. | ZENECA LTD (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021210-A1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |