Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400506 | 1.00 | TDP1 (0.34) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL7390787 | 0.84 | CYP3A4 (0.37) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL7390783 | 0.84 | CYP3A4 (0.37) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL7444000 | 0.76 | TDP1 (0.36) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL7443991 | 0.76 | TDP1 (0.36) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL9240800 | 0.76 | CYP2D6 (0.44) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL9240806 | 0.76 | CYP2D6 (0.44) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL7502619 | 0.75 | GBA1 (0.44) | MAPTKMT2ACYP3A4 | |
| SCHEMBL7502627 | 0.75 | GBA1 (0.44) | MAPTKMT2ACYP3A4 | |
| SCHEMBL397303 | 0.74 | TSHR (0.43) | TDP1TSHRMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |