Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402374 | 1.00 | HRH3 (0.50) | HRH3LTA4HNPC1RAB9AKDM4E | |
| SCHEMBL7399832 | 1.00 | HRH3 (0.50) | HRH3LTA4HNPC1RAB9AKDM4E | |
| SCHEMBL7397893 | 1.00 | HRH3 (0.50) | HRH3LTA4HNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7402514 | 0.99 | HRH3 (0.49) | HRH3LTA4HNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7404454 | 0.99 | HRH3 (0.49) | HRH3LTA4HNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7398648 | 0.99 | HRH3 (0.49) | HRH3LTA4HNPC1RAB9AKDM4E | |
| SCHEMBL7402234 | 0.97 | HRH3 (0.54) | HRH3LTA4HNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7397477 | 0.96 | HRH3 (0.53) | HRH3LTA4HNPC1RAB9AKDM4E | |
| Oxalic Acid SCHEMBL7397763 | 0.95 | KDM4E (0.54) | HRH3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7393827 | 0.93 | KDM4E (0.45) | HRH3NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637303-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | EP | claimed |
| WO-1993022302-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | claimed |
| EP-0637303-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022302-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | disclosed |