Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.85 |
| ▸ | NPY1R | P25929 | 1/20 | 0.85 |
| ▸ | NPC1 | O15118 | 3/20 | 0.82 |
| ▸ | RAB9A | P51151 | 3/20 | 0.82 |
| ▸ | HTT | P42858 | 2/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | LTA4H | P09960 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.74 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.74 |
| ▸ | HRH1 | P35367 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400512 | 1.00 | KDM4E (0.85) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL7402377 | 1.00 | KDM4E (0.85) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL7397895 | 1.00 | KDM4E (0.85) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL7399833 | 1.00 | KDM4E (0.85) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7401307 | 0.99 | KDM4E (0.83) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7398651 | 0.99 | KDM4E (0.83) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7398993 | 0.99 | KDM4E (0.83) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7404456 | 0.99 | KDM4E (0.83) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7402517 | 0.99 | KDM4E (0.83) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL7402238 | 0.99 | KDM4E (0.85) | KDM4EALDH1A1NPY1RNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637303-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | EP | claimed |
| WO-1993022302-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | claimed |
| EP-0637303-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022302-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | disclosed |