Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742360 | 0.76 | PPARG (0.50) | PPARGMEN1KMT2AALDH1A1 | |
| SCHEMBL9743417 | 0.76 | PPARG (0.50) | PPARGMEN1KMT2AALDH1A1 | |
| SCHEMBL6434393 | 0.75 | FNTA (0.40) | FNTAPGGT1BPPARGFNTBMEN1 | |
| SCHEMBL7399807 | 0.75 | STAT3 (0.31) | — | |
| SCHEMBL9665057 | 0.73 | PPARG (0.58) | PPARGALDH1A1 | |
| SCHEMBL9457080 | 0.73 | PPARG (0.58) | PPARGALDH1A1 | |
| SCHEMBL9457073 | 0.73 | PPARG (0.58) | PPARGALDH1A1 | |
| SCHEMBL9457070 | 0.73 | PPARG (0.58) | PPARGALDH1A1 | |
| SCHEMBL9742408 | 0.73 | PPARG (0.58) | PPARGALDH1A1 | |
| SCHEMBL9743833 | 0.73 | PPARG (0.58) | PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| US-5504106-A | Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |