Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821931 | 1.00 | TDP1 (0.40) | TDP1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7397762 | 0.96 | TDP1 (0.41) | TDP1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9821927 | 0.96 | TDP1 (0.41) | TDP1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9359143 | 0.87 | CHRM2 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9363885 | 0.87 | CHRM2 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9363505 | 0.85 | ATM (0.42) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7396627 | 0.85 | ATM (0.42) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7492936 | 0.85 | CHRM2 (0.37) | TDP1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9821920 | 0.84 | NPC1 (0.47) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7401003 | 0.84 | NPC1 (0.47) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491770-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-01 | — | — | EP | disclosed |
| EP-0419397-A1 | Substituted urea compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1991-03-27 | — | — | EP | disclosed |
| WO-1991003475-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-03-21 | — | — | WO | disclosed |