Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400984 | 1.00 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1ITGAVKEAP1 | |
| Hydrochloric Acid SCHEMBL8903082 | 0.99 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1ITGAVKEAP1 | |
| Hydrochloric Acid SCHEMBL8903080 | 0.99 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1ITGAVKEAP1 | |
| SCHEMBL7378810 | 0.85 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1ITGAVNAPRT | |
| SCHEMBL7506451 | 0.85 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1ITGAVNAPRT | |
| Hydrochloric Acid SCHEMBL7652844 | 0.84 | SLC1A3 (0.62) | SLC1A3SLC1A2SLC1A1ITGAVNAPRT | |
| SCHEMBL7315790 | 0.84 | POLB (0.50) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL7397814 | 0.84 | POLB (0.50) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7315786 | 0.82 | POLB (0.49) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7315781 | 0.82 | POLB (0.49) | SLC1A3SLC1A2SLC1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |