Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 6/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402674 | 0.86 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL7396739 | 0.86 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL7395686 | 0.85 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL1553532 | 0.82 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL7398425 | 0.80 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL7551863 | 0.80 | HDAC3 (0.47) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL7399456 | 0.79 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL1553512 | 0.78 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| Hydrochloric Acid SCHEMBL8602395 | 0.77 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL8602390 | 0.77 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934307-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997048697-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1997-12-24 | — | — | WO | disclosed |