Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594467 | 1.00 | KMT2A (0.50) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL29624561 | 1.00 | KMT2A (0.50) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL29624551 | 1.00 | KMT2A (0.50) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL178786 | 1.00 | KMT2A (0.50) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL30594472 | 0.99 | KMT2A (0.51) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL29624557 | 0.99 | KMT2A (0.51) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL178775 | 0.99 | KMT2A (0.51) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL178778 | 0.96 | KMT2A (0.51) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL29624572 | 0.96 | KMT2A (0.51) | KMT2AEPHX2DPP8DPP9FABP7 | |
| SCHEMBL30752687 | 0.96 | KMT2A (0.51) | KMT2AEPHX2DPP8DPP9FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300247-B | Teixobactin analogue and application thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-112300247-A | Teixobactin analogue and application thereof | 广东东阳光药业有限公司 | 2021-02-02 | — | — | CN | disclosed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |