Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25238972 | 0.85 | HTR2A (0.61) | HTR2ATAAR1HTR2C | |
| SCHEMBL29758521 | 0.80 | HTR2A (0.52) | HTR2ATAAR1HTR2CCA12CA1 | |
| SCHEMBL13753907 | 0.80 | SMN1; SMN2 (0.57) | HTR2ATAAR1HTR2CCA12CA1 | |
| SCHEMBL2294326 | 0.80 | HTR2A (0.52) | HTR2ATAAR1HTR2CCA12CA1 | |
| SCHEMBL900127 | 0.79 | HTR2A (0.52) | HTR2ATAAR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15780158 | 0.78 | HTR2A (0.48) | HTR2ATAAR1HTR2CCA12CA1 | |
| SCHEMBL31316994 | 0.78 | PDE4A (0.57) | HTR2ATAAR1HTR2CCA12CA1 | |
| SCHEMBL130898 | 0.78 | PDE4A (0.57) | HTR2ATAAR1HTR2CCA12CA1 | |
| SCHEMBL10049625 | 0.78 | HTR2A (0.48) | HTR2ATAAR1HTR2CCA12CA1 | |
| SCHEMBL131156 | 0.78 | HTR2A (0.48) | HTR2ATAAR1HTR2CCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8540904-B2 | Composition for ultraviolet absorbent substance and ultraviolet absorbent substance comprising same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20120313058-A1 | COMPOSITION FOR ULTRAVIOLET ABSORBENT SUBSTANCE AND ULTRAVIOLET ABSORBENT SUBSTANCE COMPRISING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2012-12-13 | — | — | US | disclosed |
| CN-1134412-C | N-substituted 2-cyanopyrodlidines | ��Ұ����ҩ��ʽ���� | 2004-01-14 | — | — | CN | disclosed |
| CN-1236361-A | N-substituted 2-cyanopyrrolidines | NOVARTIS AG (CH) | 1999-11-24 | — | — | CN | disclosed |
| EP-0937040-A2 | N-SUBSTITUTED 2-CYANOPYRROLIDINES | Novartis AG (CH) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998019998-A2 | N-SUBSTITUTED 2-CYANOPYRROLIDINES | NOVARTIS AG (CH) | 1998-05-14 | — | — | WO | disclosed |