Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amitrole SCHEMBL44637 | 0.82 | — | — | |
| Amitrole SCHEMBL788110 | 0.82 | HSP90AA1 (0.33) | — | |
| Amitrole SCHEMBL11334832 | 0.79 | — | — | |
| Amitrole SCHEMBL8468142 | 0.79 | — | — | |
| Amitrole SCHEMBL10550888 | 0.79 | — | — | |
| Amitrole SCHEMBL11302855 | 0.79 | — | — | |
| Amitrole SCHEMBL31379743 | 0.79 | — | — | |
| Amitrole SCHEMBL29257233 | 0.79 | — | — | |
| Amitrole SCHEMBL10399233 | 0.79 | — | — | |
| Amitrole SCHEMBL9533297 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599983-A1 | ANTI-HIV (AIDS) AGENTS | SCHERING CORPORATION (US) | 1994-06-08 | — | — | EP | disclosed |
| EP-0533342-A1 | Anti-HIV (AIDS) agents | SCHERING CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1993004043-A1 | ANTI-HIV (AIDS) AGENTS | SCHERING CORPORATION (US) | 1993-03-04 | — | — | WO | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |