Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 11/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180621 | 0.83 | F10 (0.76) | LMNAPOLBL3MBTL1F10 | |
| SCHEMBL6299410 | 0.78 | F10 (0.64) | F10MEN1KMT2A | |
| SCHEMBL5202414 | 0.78 | STS (0.57) | POLBF10 | |
| SCHEMBL5736178 | 0.78 | F10 (0.64) | F10 | |
| SCHEMBL5734353 | 0.78 | F10 (0.61) | ALDH1A1F10KMT2A | |
| SCHEMBL4942386 | 0.77 | F10 (0.70) | LMNAF10TSHRPKM | |
| SCHEMBL5735074 | 0.76 | F10 (0.68) | LMNAL3MBTL1F10TSHRPKM | |
| SCHEMBL6737341 | 0.76 | F10 (0.77) | F10 | |
| SCHEMBL5202419 | 0.76 | F10 (0.62) | LMNAALDH1A1L3MBTL1F10 | |
| SCHEMBL5736345 | 0.76 | F10 (0.68) | LMNAL3MBTL1F10TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783500-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010022-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1996-04-04 | — | — | WO | disclosed |