Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904719 | 0.79 | PRMT5 (0.48) | PPARAHSD11B1HSD11B2MAPTPPARG | |
| SCHEMBL27586082 | 0.78 | PPARG (0.49) | MEN1MAPTKMT2APPARGALDH1A1 | |
| SCHEMBL247466 | 0.78 | PPARA (0.68) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7288524 | 0.77 | KCNN4 (0.52) | PPARAHSD11B1HSD11B2MEN1CYP1A2 | |
| Dimethylamine SCHEMBL21384551 | 0.77 | PPARA (0.61) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8889149 | 0.76 | PPARA (0.66) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL7026339 | 0.76 | PPARA (0.66) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13072375 | 0.76 | PPARA (0.50) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7032523 | 0.76 | PPARA (0.66) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11127080 | 0.76 | PPARA (0.50) | PPARAMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255748-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060813-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |