SCHEMBL7401883

SCHEMBL7401883

O=C(O)CC1CCCCN1c1ccncc1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.58
PPARG P37231 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5651128 0.86 FFAR1 (0.70) FFAR1PPARG
Hydrochloric Acid SCHEMBL4055966 0.85 FFAR1 (0.68) FFAR1PPARG
SCHEMBL12707781 0.81 FFAR1 (0.76) FFAR1PPARG
SCHEMBL12707790 0.81 FFAR1 (0.76) FFAR1PPARG
SCHEMBL1584827 0.79 FFAR1 (0.68) FFAR1PPARG
SCHEMBL27504809 0.79 MEN1 (0.48) FFAR1
SCHEMBL6173007 0.77 SMN1; SMN2 (0.46)
SCHEMBL6963258 0.77 MEN1 (0.40) FFAR1
SCHEMBL6649685 0.76 CHKA (0.41) FFAR1
SCHEMBL10471976 0.76 FFAR1 (0.69) FFAR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753659-A ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, ZENECA LIMITED (GB) 1998-05-19 US disclosed
US-5750754-A TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS ZENECA LIMITED (GB) 1998-05-12 US disclosed
US-5563141-A INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION ZENECA LIMITED (GB) 1996-10-08 US disclosed
EP-0690847-A1 HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS ZENECA LIMITED (GB) 1996-01-10 EP disclosed
WO-1994022835-A2 HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS ZENECA LIMITED (GB) 1994-10-13 WO disclosed