SCHEMBL74023

SCHEMBL74023

COc1ccc2[nH]c(C)cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 1.00
ALDH1A1 P00352 4/20 0.59
HPGD P15428 2/20 0.59
PDGFRB P09619 2/20 0.59
PDGFRA P16234 2/20 0.59
LOXL2 Q9Y4K0 1/20 0.59
KDM4E B2RXH2 4/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
MAPT P10636 2/20 0.57
CA2 P00918 1/20 0.56
FLT3 P36888 6/20 0.55
CYP2A6 P11509 1/20 0.55
KEAP1 Q14145 1/20 0.55
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
TSHR P16473 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30235444 1.00 AXL (1.00) AXLALDH1A1HPGDPDGFRBPDGFRA
Formic Acid Methyl Ester SCHEMBL28167664 0.90 AXL (0.81) AXLALDH1A1HPGDPDGFRBPDGFRA
Formic Acid SCHEMBL28411328 0.90 AXL (0.81) AXLALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL16252084 0.85 AXL (0.73) AXLALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL435522 0.84 AXL (0.72) AXLALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL10771747 0.80 AXL (0.67) AXLALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL4316072 0.79 AXL (0.66) AXLALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL16756011 0.79 AXL (0.66) AXLALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL8292832 0.79 AXL (0.66) AXLALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL17175858 0.79 AXL (0.66) AXLALDH1A1HPGDPDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621214-B Antibacterial Schiff base N-acylate, and preparation method and application thereof 宜春学院 2024-04-26 CN claimed
CN-115997708-A Method for shortening release time of jellyfish dished body 中国科学院海洋研究所 2023-04-25 CN claimed
CN-109761875-B Novel method for constructing amido bond 盐城工学院 2022-07-19 CN claimed
CN-114621214-A Antibacterial Schiff base N-acylate and preparation method and application thereof 宜春学院 2022-06-14 CN claimed
CN-111253297-A Process method for preparing 5-methoxy-2-methylindole 苏州百灵威超精细材料有限公司 2020-06-09 CN claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
US-4405718-A Method and composition for urobilinogen control standard MILES LABORATORIES, INC. (US) 1983-09-20 US claimed
EP-0071766-A1 Process and composition for urobilinogen control standard MILES LABORATORIES, INC. (US) 1983-02-16 EP claimed
US-4360594-A REACTING INDOLE COMPOUND WITH SERINE, OR WITH PYRUVIC ACID AND AMMONIUM ION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-11-23 US claimed
US-4349627-A Process for producing L-tryptophan or derivatives thereof using a microorganism ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-09-14 US claimed
CN-117426383-B Application of alpha-LINDENIC ACID in inhibiting jellyfish metamorphosis development process 中国人民解放军海军军医大学 2026-05-01 CN disclosed
US-20250263760-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-08-21 US disclosed
WO-2025162967-A1 GPR50 LIGANDS FOR USE FOR TREATING DISEASES MEDIATED BY GPR50 Institut National de la Santé et de la Recherche Médicale (FR) 2025-08-07 WO disclosed
US-12319946-B2 Methods for producing modified bacteria for production of nitroaromatics UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-06-03 US disclosed
CN-120037958-A Method for killing hydroids of jellyfish by photocatalysis 中国科学院海洋研究所 2025-05-27 CN disclosed
US-4022802-A INDOLES, ALKALI HYDROXIDE; ALKYLATION CIBA-GEIGY AG (CH) 1977-05-10 US disclosed
US-4013404-A Method of dyeing hair with indolines, indoles and indazoles AMERICAN CYANAMID COMPANY (US) 1977-03-22 US disclosed
US-3980658-A SEDATIVES, TRANQUILIZERS BOEHRINGER INGELHEIM GMBH (DT) 1976-09-14 US disclosed
US-3960926-A Process for preparing azasulfonium halide salts THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-06-01 US disclosed
US-3954797-A Process for preparing azasulfonium halide salts CHROMALLOY AMERICAN CORPORATION (US) 1976-05-04 US disclosed