Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 14/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402300 | 1.00 | ACE (0.55) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7402043 | 0.98 | MAGI3 (0.57) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7402039 | 0.98 | MAGI3 (0.57) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7401397 | 0.92 | EDNRA (0.62) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7401403 | 0.92 | EDNRA (0.62) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7495581 | 0.92 | MAGI3 (0.65) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7495576 | 0.92 | MAGI3 (0.65) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7396714 | 0.89 | MAGI3 (0.63) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL7396710 | 0.89 | MAGI3 (0.63) | ACEMAGI3ECE1EDNRA | |
| SCHEMBL30838790 | 0.88 | ACE (0.67) | ACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | claimed |