Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.45 |
| ▸ | FAP | Q12884 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508058 | 0.75 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7381463 | 0.73 | DPP4 (0.55) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL6623966 | 0.73 | KDM4E (0.64) | HDAC8OPRD1PKM | |
| SCHEMBL14790806 | 0.71 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL30337959 | 0.71 | TSHR (0.63) | HDAC8OPRD1 | |
| SCHEMBL2908042 | 0.71 | TSHR (0.63) | HDAC8OPRD1 | |
| SCHEMBL7508784 | 0.70 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8365666 | 0.70 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL616963 | 0.70 | ALPI (0.61) | HDAC8ALPIPKMPTGS1XIAP | |
| SCHEMBL132790 | 0.70 | ALPI (0.61) | HDAC8ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728132-A1 | ANTITHROMBOTIC AMIDINOPHENYLALANINE AND AMIDINOPYRIDYLALANINE DERIVATIVES | PFIZER LTD (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013274-A1 | ANTITHROMBOTIC AMIDINOPHENYLALANINE AND AMIDINOPYRIDYLALANINE DERIVATIVES | PFIZER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |