Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856303 | 0.89 | F2 (0.79) | F2 | |
| SCHEMBL7403758 | 0.86 | F2 (0.61) | F2 | |
| SCHEMBL7369348 | 0.84 | F2 (0.82) | F2 | |
| SCHEMBL4904924 | 0.84 | F2 (0.67) | F2 | |
| SCHEMBL5854825 | 0.80 | F2 (0.64) | F2 | |
| SCHEMBL5855403 | 0.80 | F2 (0.71) | F2 | |
| SCHEMBL6957150 | 0.80 | F2 (0.75) | F2 | |
| SCHEMBL7372745 | 0.80 | F2 (0.75) | F2 | |
| SCHEMBL5477489 | 0.78 | F2 (0.70) | F2 | |
| SCHEMBL7403756 | 0.78 | F2 (0.68) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259506-A1 | PYRAZINONE THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6387911-B1 | Pyrazinone thrombin inhibitors | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |
| WO-2001038323-A1 | PYRAZINONE THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2001-05-31 | — | — | WO | disclosed |