Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.52 |
| ▸ | F10 | P00742 | 6/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503638 | 0.91 | F2 (0.59) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7409384 | 0.89 | F10 (0.53) | F2F10F7POLBTPSAB1 | |
| SCHEMBL7406306 | 0.87 | F2 (0.51) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7405396 | 0.86 | F2 (0.50) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7401825 | 0.85 | F10 (0.49) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7407083 | 0.83 | IDO1 (0.50) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7405379 | 0.82 | F10 (0.54) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7409890 | 0.80 | F10 (0.50) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7405073 | 0.79 | F2 (0.48) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7513930 | 0.78 | TMPRSS6 (0.51) | F2F10F7TPSAB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |