Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397197 | 0.96 | ELANE (0.74) | ELANECTRC | |
| SCHEMBL9584394 | 0.93 | ELANE (0.78) | ELANECTRC | |
| SCHEMBL9584722 | 0.89 | ELANE (0.77) | ELANECTRC | |
| SCHEMBL7400031 | 0.88 | ELANE (0.70) | ELANECTRC | |
| SCHEMBL8762836 | 0.87 | ELANE (0.75) | ELANE | |
| SCHEMBL7400161 | 0.87 | ELANE (0.72) | ELANECTRC | |
| SCHEMBL9584763 | 0.87 | ELANE (0.78) | ELANE | |
| SCHEMBL9583983 | 0.86 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL7398156 | 0.85 | ELANE (0.72) | ELANECTRC | |
| SCHEMBL7398094 | 0.85 | ELANE (0.66) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636141-B1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LTD (GB) | 1997-06-25 | — | — | EP | disclosed |
| US-5441960-A | 1-pyrimidinylacetamide human leukocyte elastate inhibitors | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| WO-1993021210-A1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |