Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403724 | 1.00 | TDP1 (0.31) | TDP1SMN1; SMN2TSHRMMEACE | |
| SCHEMBL7435219 | 0.86 | TDP1 (0.33) | TDP1MMEACE | |
| SCHEMBL7435211 | 0.86 | TDP1 (0.33) | TDP1MMEACE | |
| SCHEMBL7449289 | 0.83 | TDP1 (0.31) | TDP1 | |
| SCHEMBL9236292 | 0.83 | TDP1 (0.33) | TDP1TSHR | |
| SCHEMBL9236293 | 0.83 | TDP1 (0.33) | TDP1TSHR | |
| SCHEMBL7449297 | 0.83 | TDP1 (0.31) | TDP1 | |
| SCHEMBL7390843 | 0.83 | TDP1 (0.31) | TDP1 | |
| SCHEMBL7390844 | 0.83 | TDP1 (0.31) | TDP1 | |
| SCHEMBL7400849 | 0.82 | TDP1 (0.33) | TDP1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |