Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406124 | 0.92 | F10 (0.43) | F10PRSS1F2PLGPROC | |
| SCHEMBL7405726 | 0.92 | F10 (0.59) | F10PRSS1F2PLGPROC | |
| SCHEMBL7403864 | 0.92 | F10 (0.51) | F10PRSS1F2PLGPROC | |
| SCHEMBL7402318 | 0.85 | F10 (0.53) | F10PRSS1F2PLGPROC | |
| SCHEMBL7402421 | 0.82 | F10 (0.46) | F10PRSS1F2PROCPRSS2 | |
| SCHEMBL7401213 | 0.81 | F10 (0.40) | F10PRSS1F2PLGPROC | |
| SCHEMBL7405469 | 0.80 | PRSS1 (0.43) | F10PRSS1F2PLGPROC | |
| SCHEMBL7403509 | 0.80 | F10 (0.67) | F10PRSS1F2PLGPROC | |
| SCHEMBL7409644 | 0.80 | F10 (0.59) | F10PRSS1F2PLGPROC | |
| SCHEMBL6996683 | 0.79 | F10 (0.53) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030880-A2 | N-SUBSTITUTED AMINO ACID DERIVATIVES (FACTOR XA INHIBITORS) | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |