Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13172946 | 1.00 | OPRL1 (0.36) | OPRL1MAOBFFAR1PPARACES2 | |
| SCHEMBL740390 | 1.00 | OPRL1 (0.36) | OPRL1MAOBFFAR1PPARACES2 | |
| SCHEMBL740391 | 1.00 | OPRL1 (0.36) | OPRL1MAOBFFAR1PPARACES2 | |
| SCHEMBL7838610 | 0.86 | OPRL1 (0.44) | OPRL1 | |
| SCHEMBL6569671 | 0.86 | OPRL1 (0.44) | OPRL1 | |
| SCHEMBL5652297 | 0.86 | OPRL1 (0.44) | OPRL1 | |
| SCHEMBL10420330 | 0.86 | OPRL1 (0.44) | OPRL1 | |
| SCHEMBL6875994 | 0.85 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL13172940 | 0.75 | MDM2 (0.35) | MAOBFFAR1PPARACES2MEN1 | |
| SCHEMBL13534719 | 0.72 | OPRL1 (0.42) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |