Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.76 |
| ▸ | F10 | P00742 | 13/20 | 0.58 |
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400362 | 0.90 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL7374330 | 0.87 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL15490608 | 0.87 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL15490610 | 0.84 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL7376573 | 0.81 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL20100170 | 0.79 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL15175082 | 0.79 | F10 (0.69) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL20100168 | 0.79 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL28369185 | 0.79 | F10 (0.79) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL5792812 | 0.78 | F10 (0.64) | PDE4APDE4BPDE4CPDE4DF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707585-A1 | BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES | PFIZER INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001980-A1 | BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES | PFIZER INC. (US) | 1995-01-19 | — | — | WO | disclosed |