Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408144 | 0.92 | F2 (0.51) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7408227 | 0.89 | F2 (0.46) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6963877 | 0.86 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7527900 | 0.81 | F2 (0.42) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7408251 | 0.80 | F2 (0.40) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7449943 | 0.74 | F2 (0.53) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7113189 | 0.73 | F2 (0.57) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7409413 | 0.73 | CNR1 (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7107385 | 0.72 | F2 (0.57) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7409009 | 0.72 | F2 (0.43) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057225-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-07-25 | — | — | WO | disclosed |